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- Mutant Gene Linked to Treatment-Resistant Depression
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December 13, 2004
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Science Update
A mutant gene that starves the brain of serotonin, a mood-regulating chemical messenger, has been discovered and found to be 10 times more prevalent in depressed patients than in control subjects, report researchers funded by the National Institutes of Health’s National Institute of Mental Health (NIMH) and National Heart Lung and Blood Institute (NHLBI).
- Combination Treatment Most Effective in Adolescents with Depression
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August 17, 2004
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Press Release
A clinical trial of 439 adolescents with major depression has found a combination of medication and psychotherapy to be the most effective treatment.
- Depression Traced to Overactive Brain Circuit
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August 2, 2004
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Press Release
A brain imaging study by the NIH’s National Institute of Mental Health (NIMH) has found that an emotion-regulating brain circuit is overactive in people prone to depression—even when they are not depressed.
- “Care Managers” Help Depressed Elderly Reduce Suicidal Thoughts
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March 2, 2004
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Press Release
An intervention that includes staffing doctors' offices with depression care managers helps depressed elderly patients reduce suicidal thoughts, a study funded by NIMH has found. Martha Bruce, Ph.D., Cornell University, Charles Reynolds, III, M.D., University of Pittsburgh, and colleagues report on the outcome of the intervention in three major Eastern U.S. metropolitan areas.
- “Care Managers” Help Depressed Elderly Reduce Suicidal Thoughts
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March 2, 2004
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Press Release
An intervention that includes staffing doctors’ offices with depression care managers helps depressed elderly patients reduce suicidal thoughts, a study funded by NIH’s National Institute of Mental Health (NIMH) has found.
- Mental Illness Genetics Among Science’s Top “Breakthroughs“ for 2003
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December 22, 2003
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Press Release
Research on the genetics of mental illness, most of it NIMH-funded and much of it in the Institute’s own laboratories, was named the #2 scientific "breakthrough of the year" by Science magazine in its December l9, 2003, issue.
- Creation of New Neurons Critical to Antidepressant Action in Mice
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August 7, 2003
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Press Release
Blocking the formation of neurons in the hippocampus blocks the behavioral effects of antidepressants in mice, say researchers funded by the National Institutes of Health (NIH).
- Gene More Than Doubles Risk Of Depression Following Life Stresses
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July 17, 2003
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Press Release
Among people who suffered multiple stressful life events over 5 years, 43 percent with one version of a gene developed depression, compared to only 17 percent with another version of the gene, say researchers funded, in part, by the National Institute of Mental Health (NIMH).
- Medication and Psychotherapy Treat Depression in Low-Income Minority Women
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July 1, 2003
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Press Release
Treatment with medication or psychotherapy reduced depressive symptoms in women from minority populations, according to research funded by the National Institute of Mental Health (NIMH).
- NIMH Awards $22.6 Million for Center for Collaborative Research on Mental Disorders
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July 1, 2003
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Press Release
Under a cooperative agreement, the Center will accelerate progress toward understanding genetic origins of mental disorders including autism, schizophrenia, bipolar disorder, and depression.
